Asepsis during periodontal surgery involving oral implants and the usefulness of peri-operative antibiotics : a prospective, randomized, controlled clinical trial
Identifieur interne : 006561 ( Main/Exploration ); précédent : 006560; suivant : 006562Asepsis during periodontal surgery involving oral implants and the usefulness of peri-operative antibiotics : a prospective, randomized, controlled clinical trial
Auteurs : Mahmoud Abu-Ta'A [Belgique] ; Marc Quirynen [Belgique] ; Wim Teughels [Belgique] ; Daniel Van Steenberghe [Belgique]Source :
- Journal of clinical periodontology [ 0303-6979 ] ; 2008.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie, Antibiotique.
English descriptors
- KwdEn :
Abstract
Objectives: This randomized clinical trial compares the usefulness of pre- and post-operative antibiotics while strict asepsis was followed during periodontal surgery. Material and Methods: Two groups of 40 consecutive patients each with fully or partially edentulous jaws were enrolled. Antibiotics group (GrAB +): 23 men, mean age 60, 128 implants, received oral amoxicillin 1 g, 1 h pre-operatively and 2 g for 2 days post-operatively. Non-antibiotics group (GrAB -): 20 men, mean age 57, 119 implants, received no antibiotics. Bacterial samples were taken from the peri-oral skin before and at the end of surgery. In 12 patients in each group, samples were also taken from the nares. A VAS questionnaire evaluated symptoms of infection/ inflammation by both the patient and the periodontologist at suture removal. Results: There were no significant differences between both groups, neither for the clinical parameters nor for the microbiota. Staphylococcus aureus was detected in the nares of one patient only. The patients' subjective perception of post-operative discomfort was significantly smaller in the group receiving antibiotics. Three patients lost one or two implants. Conclusions: Antibiotics do not provide significant advantages concerning post-operative infections in case of proper asepsis. It also does not reduce peri-oral microbial contamination. It does on the other hand reduce post-operative discomfort.
Affiliations:
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Mahmoud" sort="Abu Ta A, Mahmoud" uniqKey="Abu Ta A M" first="Mahmoud" last="Abu-Ta'A">Mahmoud Abu-Ta'A</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</s1><s3>BEL</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Quirynen, Marc" sort="Quirynen, Marc" uniqKey="Quirynen M" first="Marc" last="Quirynen">Marc Quirynen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</s1><s3>BEL</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Teughels, Wim" sort="Teughels, Wim" uniqKey="Teughels W" first="Wim" last="Teughels">Wim Teughels</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</s1><s3>BEL</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Van Steenberghe, Daniel" sort="Van Steenberghe, Daniel" uniqKey="Van Steenberghe D" first="Daniel" last="Van Steenberghe">Daniel Van Steenberghe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</s1><s3>BEL</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Holder of P-1 Br?nemark Chair in Osseointegration, Catholic University of Leuven</s1><s2>Leuven</s2><s3>BEL</s3><sZ>4 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Journal of clinical periodontology</title><title level="j" type="abbreviated">J. clin. periodontol.</title><idno type="ISSN">0303-6979</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of clinical periodontology</title><title level="j" type="abbreviated">J. clin. periodontol.</title><idno type="ISSN">0303-6979</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibiotic</term><term>Clinical trial</term><term>Dentistry</term><term>Implant</term><term>Infection</term><term>Nose</term><term>Oral administration</term><term>Postoperative</term><term>Prevention</term><term>Staphylococcus aureus</term><term>Surgery</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Infection</term><term>Chirurgie</term><term>Voie orale</term><term>Implant</term><term>Antibiotique</term><term>Staphylococcus aureus</term><term>Essai clinique</term><term>Prévention</term><term>Nez</term><term>Postopératoire</term><term>Dentisterie</term><term>Traitement</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term><term>Antibiotique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives: This randomized clinical trial compares the usefulness of pre- and post-operative antibiotics while strict asepsis was followed during periodontal surgery. Material and Methods: Two groups of 40 consecutive patients each with fully or partially edentulous jaws were enrolled. Antibiotics group (GrAB <sup>+</sup>): 23 men, mean age 60, 128 implants, received oral amoxicillin 1 g, 1 h pre-operatively and 2 g for 2 days post-operatively. Non-antibiotics group (GrAB <sup>-</sup>): 20 men, mean age 57, 119 implants, received no antibiotics. Bacterial samples were taken from the peri-oral skin before and at the end of surgery. In 12 patients in each group, samples were also taken from the nares. A VAS questionnaire evaluated symptoms of infection/ inflammation by both the patient and the periodontologist at suture removal. Results: There were no significant differences between both groups, neither for the clinical parameters nor for the microbiota. Staphylococcus aureus was detected in the nares of one patient only. The patients' subjective perception of post-operative discomfort was significantly smaller in the group receiving antibiotics. Three patients lost one or two implants. Conclusions: Antibiotics do not provide significant advantages concerning post-operative infections in case of proper asepsis. It also does not reduce peri-oral microbial contamination. It does on the other hand reduce post-operative discomfort.</div></front></TEI><affiliations><list><country><li>Belgique</li></country></list><tree><country name="Belgique"><noRegion><name sortKey="Abu Ta A, Mahmoud" sort="Abu Ta A, Mahmoud" uniqKey="Abu Ta A M" first="Mahmoud" last="Abu-Ta'A">Mahmoud Abu-Ta'A</name></noRegion><name sortKey="Quirynen, Marc" sort="Quirynen, Marc" uniqKey="Quirynen M" first="Marc" last="Quirynen">Marc Quirynen</name><name sortKey="Teughels, Wim" sort="Teughels, Wim" uniqKey="Teughels W" first="Wim" last="Teughels">Wim Teughels</name><name sortKey="Van Steenberghe, Daniel" sort="Van Steenberghe, Daniel" uniqKey="Van Steenberghe D" first="Daniel" last="Van Steenberghe">Daniel Van Steenberghe</name><name sortKey="Van Steenberghe, Daniel" sort="Van Steenberghe, Daniel" uniqKey="Van Steenberghe D" first="Daniel" last="Van Steenberghe">Daniel Van Steenberghe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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